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GLP-1 Medications - Overview

GLP-1 receptor agonists are medications sometimes prescribed to people to help with weight loss and / or diabetes. People who might need a GLP-1 prescription can use Push Health to connect with a medical provider who can prescribe a medication to a patient's pharmacy when appropriate to do so.

What Are GLP-1 Medications Used For?

GLP-1 receptor agonists are prescription medicines that mimic glucagon-like peptide-1. Some GLP-1 medications are FDA-approved to improve blood sugar control in type 2 diabetes and others are approved for chronic weight management in some people. They are used together with diet and exercise. Examples of drugs that have GLP-1 drugs as a component include the following:

GLP-1 Medication Comparison

Product Ingredient Receptors Labeled Use Form
Zepbound Tirzepatide GIP / GLP-1 Weight managment; OSA Injection
Wegovy Semaglutide GLP-1 Weight management, CV risk Injection / Tablet
Foundayo Orforglipron GLP-1 Weight managment Tablet
Ozempic Semaglutide GLP-1 Type 2 diabetes; selected heart / kidney Injection
Mounjaro Tirzepatide GIP / GLP-1 Type 2 diabetes Injection
Rybelsus Semaglutide GLP-1 Type 2 diabetes Tablet
Saxenda / Victoza Liraglutide GLP-1 Diabetes / weight Injection

GLP-1 receptor agonists are prescription medications that mimic glucagon-like peptide-1. These medications are thought to work by modulating insulin secretion and glucose levels, gastric emptying and reducing food intake. These mechanisms help contribute to weight loss and appetite suppression. GLP-1 receptors are found throughout the body in areas such as the pancreatic beta cells and ducts, gastric mucosa, lungs, heart, kidneys, immune cells, and hypothalamus. The secondary benefits of the effects of GLP-1 drugs may also be improvements in lipotoxicity due to reductions in fat distribution.

GLP-1 Medications - Cost and Dosage

Some people may find GLP-1 online medications to be moderately expensive - ranging from hundreds to thousands of dollars - when paying out of pocket. Some manufacturers may offer GLP-1 medication coupons and GLP-1 drug prescription savings cards may also help reduce out-of-pocket costs for GLP-1 prescription medications when buying GLP-1 drugs at a pharmacy. Patients may also find insurance will cover some or all costs associated with the medications although reimbursement patterns are constantly changing.

The GLP-1 medication dosage and regimen used depends on the exact drug being used, the judgment of the prescribing medical provider, and the health needs of the patient. Typically, more than one of these medications should not be used at once.

Can I Buy GLP-1 Medication Online?

GLP-1 medications require a prescription to be dispensed by a pharmacy in the United States. People who might need a GLP-1 drug prescription can use Push Health to connect with a medical provider who can prescribe a medication when appropriate to do so.

Frequently Asked Questions about GLP-1 Medications

What is a GLP-1 medication?

GLP-1 (glucagon-like peptide-1) medications are a class of prescription drugs that mimic or stimulate a hormone naturally produced in the body and can help increase insulin secretion, slow gastric emptying, and reduce food intake and appetite for the purpose of weight loss and blood sugar control in some people.

What is the difference between Ozempic, Wegovy, Mounjaro, Zepbound, and Foundayo?

Ozempic and Wegovy both contain semaglutide - a GLP-1 receptor agonist. Ozempic is FDA-approved for type 2 diabetes while Wegovy is FDA-approved for weight management. Mounjaro and Zepbound both contain tirzepatide - a dual GLP-1/GIP agonist. Mounjaro is approved for diabetes while Zepbound for weight management. Foundayo (orforglipron) is a small-molecule oral GLP-1 agonist approved for weight management.

Is there an oral GLP-1 medication?

Yes. There are now multiple oral options, including Foundayo (orforglipron), Rybelsus (semaglutide), and Wegovy (semaglutide).

What are the most common side effects of GLP-1 medications?

The most common side effects are gastrointestinal symptoms such as nausea, diarrhea, vomiting, and constipation. These symptoms are most pronounced when starting the medication or during dose increases and usually diminish over time. Other side effects include injection site reactions (for injectable forms), headache, and fatigue. Rare but serious side effects include pancreatitis, gallbladder disease, and kidney injury.

Do GLP-1 medications cause muscle loss?

Some muscle loss has been reported alongside fat loss in clinical trials. To minimize this, providers typically recommend adequate protein intake and resistance exercise during treatment.

GLP-1 Medications - Side Effects

GLP-1 medications can cause side effects when used, including nausea, vomiting, and injection site reactions (for injectable versions) such as pain and swelling. The majority of reported side effects tend to be gastrointestinal in nature although skeletal muscle loss has also been reported. The medications should typically not be prescribed when there is a history of certain types of familial endocrine disorders or thyroid cancer. Alcohol should be minimized or not used at all while taking the medication. Possible risks associated with the use of GLP-1 medications during surgery are also being studied. People with an allergy to the medication class should avoid them. Discuss any questions or concerns with a qualified medical provider.

How to Get a GLP-1 Prescription with Push Health

  1. Complete a brief health intake. Answer questions about your weight history or diabetes, BMI, current medications, relevant medical conditions.
  2. Connect with a licensed medical provider. A provider will review your information and evaluate which medication is most appropriate for your situation. Same-day consultations are available.
  3. Receive your prescription. When appropriate, your provider will send a prescription to a pharmacy or manufacturer direct-to-patient program of your choice. No office visit is required.
  4. Begin treatment. GLP-1 medications range in price. Manufacturer savings programs and insurance may significantly reduce out-of-pocket costs.

No health insurance or subscription is required. Medical providers are available now.

More GLP-1 Drug Information

Last updated October 8, 2026. Given the evolving nature of medicine and science, this information might not be accurate and should not be construed as medical advice or diagnosis / treatment recommendations. Please consult a licensed medical provider if you have additional questions. Please call 911 immediately or go to the nearest emergency room if you believe you are experiencing a medical emergency.