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Hormone Replacement Therapy (HRT) - Overview
Hormone replacement therapy (HRT) consists of one or more medications that are sometimes prescribed to people who are experience symptoms related to hormonal imbalances. People who might need hormone replacement therapy prescriptions can use Push Health to connect with a medical provider who can prescribe hormone replacement therapy medications when appropriate to do so. Please note that Push Health does not prescribe testosterone medication at this time.
What Is Hormone Replacement Therapy?
Hormone replacement therapy prescription medications are sometimes prescribed to people who need hormone medications to help with symptoms related to hormonal imbalances. Typically, prescribed hormone replacement medications include estradiol and progesterone although other medications are sometimes included in the regimen.
Why Is Hormone Replacement Therapy Prescribed?
Hormone replacement therapy medications are frequently prescribed for women who are in perimenopausal or menopausal stages of life. During these life stages, women often experience vasomotor symptoms that can manifest in a variety of ways such as hot flashes, insomnia, anxiety, and mood instability as well as irregular bleeding. Hormone replacement medication treatment is thought to work by replacing and stabilizing fluctuating hormonal levels, often due to aging. Other benefits of hormone replacement therapy may include osteoporosis and endometrial hyperplasia risk reduction.
HRT Medications - Dosage and Cost
The hormone replacement medication dosage and regimen used depends on the judgement of the prescribing medical provider and the health needs of the patient. Some people may find hormone replacement medications to be moderately expensive when paying out of pocket, even when using hormone medication savings coupons, because hormone replacement treatment needs to be used monthly. Some insurance plans may help cover costs associated with hormone replacement prescription medications when buying hormone medications at the pharmacy.
Can I Buy Hormone Replacement Medications Online?
Typical hormone replacement medications require a prescription to be dispensed by a pharmacy in the United States. For this reason, hormone replacement medications OTC (over the counter) are not available and one cannot just buy hormones online. The first step to getting a hormone replacement medications is consulting a licensed medical provider. People who might need hormone replacement can use Push Health to connect with a medical provider who can prescribe hormone medications when appropriate to do so. Please note that Push Health cannot prescribe testosterone at this time.
Frequently Asked Questions about HRT
What is hormone replacement therapy?
Hormone replacement therapy (HRT) is prescription medication - typically estradiol and progesterone - that replaces or supplements hormones that have declined during perimenopause and menopause. HRT is the most effective treatment for hot flashes, night sweats, sleep disturbances, mood changes, vaginal dryness, and other symptoms caused by declining estrogen and progesterone levels.
Who is a good candidate for HRT?
HRT is generally appropriate for women in perimenopause or menopause who are experiencing significant symptoms affecting quality of life and who do not have contraindications. According to current guidelines, healthy women under 60 or within 10 years of menopause onset are generally good candidates. Women who had their ovaries removed surgically (oophorectomy) before natural menopause are particularly strong candidates. A licensed provider will evaluate individual history and risk factors during a consultation.
What is the difference between bioidentical and synthetic hormones?
Bioidentical hormones are chemically identical to the hormones naturally produced by the body. Estradiol and progesterone used in HRT today are bioidentical. Synthetic hormones - such as conjugated equine estrogen and medroxyprogesterone acetate - have different molecular structures. Most current HRT prescriptions use bioidentical estradiol and progesterone, which have a better-established safety profile than older synthetic formulations.
Do I need progesterone with estradiol?
Women with an intact uterus who take systemic estradiol need progesterone to protect the uterine lining. Estrogen alone can cause endometrial hyperplasia and increases the risk of uterine cancer over time. Women who have had a hysterectomy typically do not need progesterone. Women using only local vaginal estrogen for vaginal dryness typically do not need systemic progesterone.
Is HRT safe?
For most healthy women under 60 or within 10 years of menopause onset, modern bioidentical HRT is considered safe and effective when prescribed appropriately. The February 2026 FDA removal of the black box warning from bioidentical estradiol patches, gels, and creams reflects the current evidence base. HRT is not appropriate for women with certain contraindications, including active estrogen-sensitive cancer, active blood clots, or liver disease. A provider will evaluate individual risk factors before prescribing.
Can I get HRT online without an office visit?
Yes. Through Push Health, women who need HRT prescriptions can connect with a licensed medical provider online to discuss their symptoms and receive a prescription for estradiol, progesterone, or combination hormone therapy when appropriate - without an in-person office visit. Prescriptions are sent electronically to a pharmacy of the patient's choice.
Hormone Replacement Therapy - Side Effects
Hormone replacement therapy prescription medications can cause side effects when used, including weight gain, abnormal bleeding, mood disorders, depression, breast tenderness, nausea and headaches. However, resurgent interest in hormone replacement therapy has resulted from reassessment of the actual risks that might occur from treatment. Before using hormone replacement medications, it is important to discuss potential side effects and other concerns with a qualified medical provider. Hormone replacement therapy and alcohol should not be used together. People with a hypersensitivity or allergy to hormone replacement medications or similar medications should not use hormone replacement.
How to Get Hormone Replacement Therapy with Push Health
- Complete a brief health intake. Answer a few questions about your symptoms, menstrual history, current medications, and relevant medical history - including any personal or family history of breast cancer, blood clots, or cardiovascular disease.
- Connect with a licensed medical provider. A provider will review your information and evaluate which HRT medications and delivery forms are most appropriate for your situation. Same-day consultations are available.
- Receive your prescription electronically. If HRT is appropriate, your provider will send prescriptions for estradiol, progesterone, or a combination product to a pharmacy of your choice - no office visit required.
- Pick up your medication. Generic estradiol and progesterone are available at most retail pharmacies at affordable prices. Gels, sprays, and oral tablets remain widely available and are not affected by the current estradiol patch shortage. No health insurance or subscription is required.
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Last updated August 5, 2026. Given the evolving nature of medicine and science, this information might not be accurate and should not be construed as medical advice or diagnosis / treatment recommendations. Please consult a licensed medical provider if you have additional questions. Please call 911 immediately or go to the nearest emergency room if you believe you are experiencing a medical emergency.