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Losartan - Summary
Losartan, found in the form losartan potassium in the branded version Cozaar, is an angiotensin II receptor antagonist medication used in the treatment of hypertension. People in need of a losartan prescription can connect with a licensed medical provider through Push Health who can prescribe losartan potassium medication, including losartan 50 mg and losartan 100 mg tablets, when appropriate to do so.
What Is Losartan Used For?
Losartan prescription medication is an oral medication used to treat high blood pressure. Losartan medication, like candesartan (Atacand), irbesartan (Avapro), olmesartan (Benicar), telmisartan (Micardis) and valsartan (Diovan), belongs to a class of medications known as an angiotensin II receptor blockers (ARBs). Losartan works by blocking the binding of angiotensin II to AT1 receptor in tissues, thereby impairing the aldosterone-secreting and vasoconstrictor effects of angiotensin II. Losartan potassium can be used alone or in combination with other antihypertensive agents such as diuretics to treat hypertension. Losartan may also help reduce the risk of stroke and left ventricular hypertrophy in specific classes of patients and help with the management of diabetic nephropathy. Losartan prescription tablets are also utilized in combination with hydrochlorothiazide in the medication Hyzaar.
Losartan - Cost and Coupons
Generic losartan medication is considered an affordable medication, costing under thirty cents per pill at most pharmacies. In addition, many insurance plans may cover the cost of the medication completely. At this time, however, losartan requires a prescription and losartan OTC is not available in the United States. Losartan coupons may also be available to reduce the cost for people paying out of pocket and some insurance plans may help cover costs associated with a losartan prescription when buying losartan tablets at the pharmacy.
Losartan - Dosage
Losartan potassium is a white to off-white crystalline powder. For dosing, available forms of losartan are orally administered losartan 25 mg tablets, losartan 50 mg tablets and losartan 100 mg tablets. After oral administration, losartan is partially converted into an active carboxylic acid metabolite and other inactive metabolites. The terminal half-life of losartan tablets after oral administration is about two hours. After oral administration, less than 20% of the dose is converted to the active metabolite and losartan is excreted via the urine and the bile. Losartan and its metabolite bind extensively to proteins like albumin in the plasma. Losartan may be administered with food or other hypertensive agents. Losartan tablets should generally be stored at 25° C but check the package insert for exact instructions.
Can I Buy Losartan Online?
Losartan medication is a prescription medication in the US. In other words, one cannot legally buy losartan online or walk into a pharmacy to buy the medication without a prescription. People who need a losartan prescription, however, can connect with a licensed medical provider through Push Health who can prescribe losartan medication, including generic losartan 50 mg and losartan 100 mg tablets, when appropriate to do so.
Frequently Asked Questions about Losartan
What is losartan used for?
Losartan is an angiotensin II receptor blocker (ARB) used to treat high blood pressure (hypertension), slow the progression of kidney disease in patients with type 2 diabetes and proteinuria, and reduce the risk of stroke in patients with hypertension and left ventricular hypertrophy. It works by blocking the AT1 receptor for angiotensin II - preventing the blood vessel constriction and fluid retention that raise blood pressure.
Is losartan the same as lisinopril?
No, though both are commonly prescribed for high blood pressure and kidney protection. Lisinopril is an ACE inhibitor; losartan is an ARB. Both act on the renin-angiotensin-aldosterone system but at different points. The key practical difference is that lisinopril causes a persistent dry cough in 5–35% of patients - a side effect that ARBs like losartan do not cause. Losartan is the most common first-line alternative for patients who develop a cough on lisinopril. They should not be taken together.
Does losartan cause a cough?
No. ARBs such as losartan do not cause the persistent dry cough associated with ACE inhibitors like lisinopril. This is one of the most clinically important differences between the two drug classes. The cough caused by ACE inhibitors results from bradykinin accumulation - a mechanism specific to ACE inhibition that does not occur with AT1 receptor blockade.
Can I stop taking losartan suddenly?
No - not without consulting your provider. Stopping losartan abruptly can cause blood pressure to rise, sometimes significantly. If losartan needs to be reduced or discontinued, this should be done under provider supervision. Always contact your provider before making any changes to your losartan regimen.
What foods should I avoid while taking losartan?
Patients on losartan should be cautious with high-potassium foods - including bananas, potatoes, oranges, spinach, tomatoes, and salt substitutes that contain potassium chloride - because losartan can raise blood potassium levels. Excessive alcohol should be avoided as it can lower blood pressure and worsen dizziness. NSAIDs such as ibuprofen and naproxen should be used minimally, as they can reduce losartan's effectiveness and increase kidney strain.
Is losartan safe during pregnancy?
No. Losartan is contraindicated in pregnancy. Like ACE inhibitors, ARBs can cause serious harm to the developing fetus during the second and third trimesters — including kidney malformation, reduced amniotic fluid, and neonatal death. Women who are pregnant or planning to become pregnant should not take losartan. Women of childbearing age taking losartan should use effective contraception and discuss any pregnancy plans with their provider immediately.
Can losartan cause kidney problems?
In patients with normal kidney function, losartan is kidney-protective - particularly in people with diabetes and proteinuria. However, losartan can cause or worsen kidney problems in certain situations: patients with significant pre-existing kidney disease, bilateral renal artery stenosis, or those who become severely dehydrated may experience a decline in kidney function. Regular monitoring of kidney function and potassium levels is recommended for patients on losartan.
What is the difference between losartan and valsartan?
Losartan and valsartan are both ARBs used for hypertension. Losartan has the additional FDA-approved indications for diabetic nephropathy and stroke risk reduction in hypertension with left ventricular hypertrophy. Losartan is generally considered one of the best-studied ARBs with a well-established evidence base. The right choice between ARBs depends on the specific indication, patient profile, and provider judgment.
How much does losartan cost?
Generic losartan is one of the most affordable blood pressure medications available - typically under 30 cents per tablet at most pharmacies. A standard 30-day supply of losartan 50 mg costs well under $15 at most retail pharmacies. Prescription savings cards can help reduce costs further for patients paying out of pocket.
Can I take losartan with other blood pressure medications?
Yes - losartan is commonly used in combination with other antihypertensive medications. It is frequently combined with hydrochlorothiazide (as in the combination product Hyzaar) and with calcium channel blockers such as amlodipine. Losartan should not be combined with ACE inhibitors (such as lisinopril) or other ARBs, as these combinations increase the risk of kidney injury, hyperkalemia, and hypotension without additional blood pressure benefit for most patients.
Losartan - Side Effects
Losartan prescription tablets, like similar medications, can cause side effects in some people. Side effects from losartan prescription medication use include, but are not limited to, nausea, diarrhea, angioedema, fatigue, edema, abdominal pain, insomnia and cough. All questions regarding side effects associated with losartan medication use should be discussed with one's pharmacist and medical provider before use. Losartan medication and alcohol should generally not be used together. People with a hypersensitivity to losartan medication or similar drugs should avoid using losartan prescription tablets.
How to Get a Losartan Prescription with Push Health
- Complete a brief health intake. Answer a few questions about your blood pressure history, current medications, kidney function, and any relevant medical conditions - including whether you previously experienced a cough on lisinopril or another ACE inhibitor.
- Connect with a licensed medical provider. A provider will review your information and evaluate whether losartan is appropriate for your situation. Same-day consultations are available.
- Receive your prescription electronically. If losartan is appropriate, your provider will send a prescription to a pharmacy of your choice - no office visit required.
- Pick up your medication same day. Generic losartan is available at most retail pharmacies, typically under $15 for a 30-day supply. No health insurance or subscription is required.
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Last updated August 4, 2026. Given the evolving nature of medicine and science, this information might not be accurate and should not be construed as medical advice or diagnosis / treatment recommendations. Please consult a licensed medical provider if you have additional questions. Please call 911 immediately or go to the nearest emergency room if you believe you are experiencing a medical emergency.