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Prednisone - Overview
Prednisone is a prescription medication used to reduce inflammation and suppress overactive immune responses in certain conditions. Push Health can help people who might need a prednisone prescription connect with a medical provider who can prescribe the medication when appropriate to do so.
What Is Prednisone Used For?
Prednisone belongs to a class of medications known as corticosteroids and is used to reduce inflammation and suppress overactive immune responses in certain conditions. The medication is primarily used to reduce the amount of inflammation in the body. Prednisone may be prescribed for a broad range of conditions, including:
- Allergic reactions - contact dermatitis, hives and poison ivy
- Arthritis - rheumatoid and psoriatic arthritis
- Asthma and COPD exacerbations
- Autoimmune conditions - lupus and inflammatory bowel disease
- Gout flares
- Sinus inflammation - acute bacterial sinusitis with swelling
- Skin conditions - eczema, bullous pemphigoid, and other inflammatory dermatoses
Prednisone is typically prescribed in generic form and has also been marketed under the names Deltasone, Rayos, Sterapred and others. Prednisone is synthetic and is derived from cortisone. It is also used in the management of some people with nephrotic syndrome. The medication is similar to dexamethasone (Decadron), hydrocortisone and methylprednisolone (Medrol Dosepak) in activity.
Prednisone - Dosage and Cost
Prednisone tablets are generally available in strengths of 1 mg, 2.5 mg, 5 mg, 10 mg, 20 mg, and 50 mg. Short-course regimens for acute flares often use 20-60 mg daily for several days, sometimes with a taper over days to weeks. Chronic disease may use much lower daily doses. Ultimately, the dose and protocol depends on the condition being treated and the prescribing provider's judgment. It is typically recommended that the medication be taken in the morning with food when possible to limit insomnia and stomach upset. Do not change or stop a multi-week course on your own.
Generic prednisone is considered affordable, costing under thirty cents per pill at many pharmacies in the United States. Branded versions are more expensive. In some cases, insurance may help with medication costs. Prescription discount cards may also be available online.
Can I Buy Prednisone Online?
Prednisone is a prescription medication in the United States and is not available over-the-counter. Push Health can help people who need a prednisone prescription connect with a licensed medical provider who can prescribe the medication to a local or delivery pharmacy when appropriate to do so.
Prednisone - Frequently Asked Questions
What conditions is prednisone medication used to treat?
Prednisone is used to treat inflammatory and immune-related conditions such as severe allergies, asthma/COPD flares, arthritis flares, and selected skin or autoimmune diseases.
How quickly does prednisone work?
Anti-inflammatory effects often begin within a few hours. Many people feel better within 48 hours, depending on the condition being treated and the dose.
How long does prednisone stay in the system?
Prednisone has a plasma elimination half-life of approximately 3 hours, but its biological half-life is approximately 18–36 hours. This longer biological activity is why it can often be dosed once daily despite its short plasma half-life.
Can prednisone raise blood sugar?
Yes. People with diabetes may need closer monitoring or temporary medication adjustments.
Is prednisone a steroid medication?
Yes. Prednisone is a corticosteroid medication used to reduce inflammation. It is not an anabolic steroid used for muscle building.
Is prednisone a controlled substance?
No.
Is prednisone available in generic form?
Yes. Generic prednisone medication is widely available and typically inexpensive.
What is the difference between prednisone and prednisolone?
Prednisone is a prodrug that is converted by the liver into prednisolone. Prednisolone is sometimes preferred when liver function is impaired.
Why do some courses need a taper?
Longer courses can suppress the body’s own cortisol production. Gradual dose reduction lowers the chance of withdrawal-type symptoms. Short bursts may not always need a taper but discuss your situation with your medical provider.
Can I drink alcohol while taking prednisone?
Alcohol should generally not be consumed while taking the medication as it can worsen stomach irritation and affect blood sugar levels.
Is prednisone covered by insurance?
Prednisone is sometimes covered by insurance (check with your plan) and the self-pay costs are typically affordable.
Prednisone - Side Effects
Common short-course side effects from prednisone use include increased appetite, fluid retention, insomnia, mood changes, and higher blood sugar. Other side effects can occur when prednisone is used at a higher dose or for a longer period of time:
- Infection
- Bone loss
- Weight gain
- Higher blood pressure
- Stomach irritation (worse with NSAIDs)
- Adrenal suppression if a long course is stopped suddenly
Avoid live vaccines during high-dose or prolonged therapy unless a medical provider says otherwise. Older adults may face higher risks of infection, glucose rise, bone loss, and confusion. Seek care for severe mood changes, black stools, vision changes, or signs of serious infection. Prednisone withdrawal is another side effect and a taper is often done after a long period of use.
While taking prednisone, alcohol can irritate the stomach lining and affect blood sugar levels. People with a known hypersensitivity to prednisone should avoid using it. Direct any questions to your medical provider.
How To Get Prednisone at Push Health
- Submit your health history. Answer a few questions about your health, why you're seeking prednisone, current medications, and relevant medical history.
- Connect with a licensed medical provider online. A medical provider will review your request and connect with you.
- Receive your prescription. When appropriate, your medical provider will send your prescription to the pharmacy of your choice.
- Pick up your medication or have it delivered. Generic prednisone is available at most retail pharmacies and typically costs under 30 cents per tablet. No health insurance or subscription is required.
No health insurance or subscription is required. Medical providers are available now.
More Prednisone Information
Last updated September 30, 2026. Given the evolving nature of medicine and science, this information might not be accurate and should not be construed as medical advice or diagnosis / treatment recommendations. Please consult a licensed medical provider if you have additional questions. Please call 911 immediately or go to the nearest emergency room if you believe you are experiencing a medical emergency.