Qlosi Prescription Online
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Qlosi - Overview
Qlosi is a medication sometimes prescribed to people who need medication for presbyopia (age-related farsightedness). People who might need a Qlosi prescription can use Push Health to connect with a medical provider who can prescribe Qlosi medication when appropriate to do so.
What Is Qlosi Used For?
Qlosi prescription medication contains the active ingredient pilocarpine. Qlosi medication is sometimes prescribed to people who need treatment for presbyopia (age-related farsightedness) - an age-related condition in which the eye's crystalline lens gradually loses the flexibility needed to focus on near objects. Presbyopia affects most adults over 45 and is the reason many people need reading glasses. Qlosi contains pilocarpine 0.4% as its active ingredient and is FDA-approved for the improvement of near vision in adults with presbyopia. Pilocarpine is a muscarinic agonist that works by contracting the iris sphincter muscle leading to constriction of the pupil of the eye. This pupil constriction creates a pinhole effect that extends depth of focus and improves the ability to see objects up close without relying on reading glasses or bifocals. Qlosi is one of three prescription presbyopia eye drops currently available in the United States, alongside Vuity (pilocarpine 1.25%) and Vizz (aceclidine 1.44%).
Qlosi vs. Vuity and Vizz - How Do They Compare?
Qlosi, Vuity, and Vizz are all FDA-approved prescription eye drops for presbyopia, but they differ in active ingredient, dose, mechanism, and side effect profile.
Qlosi vs. Vuity. Both Qlosi and Vuity contain pilocarpine, but at different concentrations. Vuity uses the higher 1.25% pilocarpine concentration and produces stronger pupil constriction but potentially more myopic shift (distance blur) in some patients. Qlosi uses the lower 0.4% concentration with the intention of providing effective near vision improvement with a reduced tendency to blur distance vision. Patients who tried Vuity and experienced significant distance blur may find Qlosi's lower-dose formulation better tolerated.
Qlosi vs. Vizz. Vizz (aceclidine 1.44%) uses a different active ingredient entirely - aceclidine rather than pilocarpine. Aceclidine is a predominantly pupil-selective muscarinic agonist that contracts the iris sphincter with minimal stimulation of the ciliary muscle and produces near vision improvement with very little myopic shift. Vizz is also once-daily and lasts up to 10 hours. Patients who want to minimize distance blur may prefer Vizz over either pilocarpine-based option.
Qlosi - Dosage and Cost
Qlosi is typically administered as one drop in each eye once daily. A second drop is sometimes used 2 to 3 hours after the first dose for extended near vision effect up to 8 hours. Qlosi medication should be used as directed by the prescribing provider. Qlosi is a branded prescription medication and out-of-pocket pricing varies by pharmacy with prices ranging from $80-90 for 30 0.4 mL of 0.4% vials (1 carton). Patients should check with their insurer or use a prescription savings card to confirm current costs. Some insurance plans may cover Qlosi when prescribed for presbyopia.
Can I Buy Qlosi Online?
Qlosi requires a prescription to be dispensed by a pharmacy in the United States. For this reason, Qlosi OTC is not available and one cannot just buy Qlosi online. The first step to getting a Qlosi prescription is consulting a licensed medical provider. People who might need a Qlosi prescription can use Push Health to connect with a medical provider who can prescribe Qlosi medication when appropriate to do so.
Qlosi - Frequently Asked Questions
What is Qlosi used for?
Qlosi is an FDA-approved prescription eye drop for the treatment of presbyopia - the age-related loss of near-focusing ability that typically begins around age 45. It contains pilocarpine 0.4% and works by constricting the pupil of the eye to create a pinhole effect that extends depth of focus and improves near vision.
Is Qlosi the same as Vuity?
Both Qlosi and Vuity contain pilocarpine, but at different concentrations. Vuity contains 1.25% pilocarpine; Qlosi contains 0.4% pilocarpine. The lower concentration in Qlosi is designed to provide near vision improvement with less myopic shift (distance blur) than the higher-dose Vuity. Vuity is taken once daily; Qlosi can be taken once or twice daily.
How does Qlosi compare to Vizz?
Vizz uses a different active ingredient — aceclidine 1.44% — rather than pilocarpine. Aceclidine is predominantly pupil-selective, contracting the iris with minimal ciliary muscle stimulation, which produces near vision improvement with very little to no myopic shift (distance blur). Vizz is also once-daily and lasts up to 10 hours. Patients particularly sensitive to distance blur may prefer Vizz; Qlosi offers an alternative for those who want a lower-dose pilocarpine option.
Does Qlosi cause blurry distance vision?
Qlosi may cause some transient blurring of distance vision - particularly in dim light or immediately after instillation - due to the pupil constriction it produces. However, the 0.4% pilocarpine concentration in Qlosi is specifically designed to minimize this effect compared to the higher-dose Vuity (1.25%). The degree of distance blur varies between patients.
How quickly does Qlosi work and how long does it last?
Qlosi typically begins working within 15 to 30 minutes of instillation and can provide near vision improvement for up to 6 to 8 hours. A second drop may be used 2 to 3 hours after the first for extended effect throughout the day.
Can I get a Qlosi prescription online?
Yes. Through Push Health, people who need a Qlosi prescription can connect with a licensed medical provider who can evaluate their presbyopia symptoms and prescribe Qlosi eye drops when appropriate — without an office visit. Prescriptions are sent electronically to a pharmacy of the patient's choice.
Qlosi - Side Effects
Qlosi prescription medication can cause side effects when used. The most common side effect is transient blurry vision immediately after instilling the drop, potentially affecting distance vision and limiting activities such as driving while the drop is active. Headache and eye redness or irritation have also been reported. These side effects are generally mild and relate to pilocarpine's pupil-constricting mechanism. Patients with a history of retinal detachment, narrow-angle glaucoma, or other conditions that may be exacerbated by pupil constriction should discuss these conditions with their medical provider before using Qlosi eye drops. Patients with a known hypersensitivity to pilocarpine or any component of the Qlosi formulation should not use this medication. Alcohol does not have a documented pharmacokinetic interaction with pilocarpine eye drops but patients should discuss alcohol use and any other health concerns with their medical provider prior to starting Qlosi medication.
How to Get a Qlosi Prescription with Push Health
- Complete a brief health intake. Answer a few questions about your vision, age, current use of reading glasses or contact lenses, and any relevant eye health history - including any history of glaucoma or retinal conditions.
- Connect with a licensed medical provider. A provider will review your information and evaluate whether Qlosi is appropriate - or whether another presbyopia eye drop such as Vizz or Vuity might be a better fit. Same-day consultations are available.
- Receive your prescription electronically. If Qlosi is appropriate, your provider will send a prescription to a pharmacy of your choice - no office visit required.
- Begin treatment. One drop in each eye once daily. A second drop may be used after 2 to 3 hours for extended effect.
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More Qlosi Information
Last updated August 4, 2026. Given the evolving nature of medicine and science, this information might not be accurate and should not be construed as medical advice or diagnosis / treatment recommendations. Please consult a licensed medical provider if you have additional questions. Please call 911 immediately or go to the nearest emergency room if you believe you are experiencing a medical emergency.