Xofluza Prescription Online
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Xofluza - Overview
Xofluza is a prescription antiviral medication used in the treatment of acute, uncomplicated influenza in adult patients. People who might need a Xofluza prescription can use Push Health to connect with a medical provider who can prescribe the medication to a local or delivery pharmacy when appropriate to do so.
What Is Xofluza Used For?
Xofluza contains the active ingredient baloxavir marboxil is sometimes indicated for the treatment of acute uncomplicated influenza. It is typically prescribed to otherwise healthy people with flu-like illness during influenza season when treatment is appropriate and started early. At times, it might be used for post-exposure prevention after contact with someone who has the flu.
Xofluza belongs to a class of medications known as polymerase acidic (PA) endonuclease inhibitors. Xofluza is thought to work by blocking the enzymatic activity of a protein in the influenza virus through helping to block gene transcription. The effect of the medication is to impair the ability of the influenza virus to replicate itself although some influenza viruses have demonstrated resistance to Xofluza due to the presence of amino acid substitutions in the target protein.
Xofluza works differently than oseltamivir (Tamiflu) which is a neuraminidase inhibitor taken for several days. Neither medication will treat bacterial infections that coexist with influenza infections.
Xofluza vs. Tamiflu
| Feature | Xofluza (baloxavir) | Tamiflu (oseltamivir) |
|---|---|---|
| Dosing | Usually one dose | Twice daily for 5 days |
| Best start | Within 48 hours of symptoms | Within 48 hours of symptoms |
| Food | With or without food (avoid cations) | With food may ease stomach upset |
| Cost | Often higher cash price | Generic usually cheaper |
| Class | Polymerase acidic endonuclease inhibitor | Neuraminidase inhibitor |
Xofluza does not treat COVID-19, the common cold, or bacterial infections that can follow the flu. A medical provider can help choose the appropriate medication based on the symptoms and medical history.
Xofluza - Dosage and Cost
Xofluza is generally prescribed as a single dose (typically 40 mg or 80 mg) taken orally within 48 hours of the start of symptoms. Xofluza is typically available as 20 mg and 40 mg tablets and should be taken exactly as prescribed. Xofluza should not be taken at the same time as antacids, calcium-rich supplements, iron, magnesium, zinc, selenium, and some laxatives (consult a pharmacist for exact instructions).
Branded Xofluza is expensive, costing almost $160 for a Xofluza 80 mg dose pack without coverage. Insurance and manufacturer coupons may help with costs associated with the medication.
Can I Buy Xofluza Online?
Xofluza requires a prescription to be obtained in the United States. People who need a Xofluza prescription can use Push Health to connect with a medical provider who can prescribe the medication to a local pharmacy when appropriate to do so.
Frequently Asked Questions about Xofluza
What is Xofluza used for?
Xofluza is used for single-dose treatment of some cases of acute uncomplicated influenza and selected post-exposure prevention.
How soon do I need to take Xofluza?
As soon as possible and ideally within 48 hours of symptom onset. Later doses help much less.
Is Xofluza an antibiotic?
No. It is an influenza antiviral.
Can I take Xofluza with vitamins or antacids?
Not at the same time if they contain polyvalent cations (e.g. calcium, iron, magnesium, zinc).
Does Xofluza replace the flu vaccine?
No. Vaccination remains the main prevention tool.
How much does Xofluza cost?
The medication can be expensive when paying out of pocket. Generic versions are usually cheaper when appropriate.
Xofluza - Side Effects
Xofluza can cause side effects such as nausea, diarrhea, headache and bronchial symptoms. Xofluza should not be used at the same time as polyvalent cation-containing laxatives, antacids, or supplements such as calcium, magnesium, zinc, iron or selenium.
As an antiviral medication, Xofluza can affect influenza vaccines that contain live viruses. Serious allergic reactions are rare but people who do have a hypersensitivity should not use the medication. Discuss any concerns with a licensed medical provider before using the medication and seek emergency care for trouble breathing, swelling, or severe rash.
How to Get Xofluza with Push Health
- Complete a brief health intake. Describe when your symptoms started and flu exposures, relevant conditions such as asthma, and any supplements or antacids that you take.
- Connect with a licensed medical provider. A provider will review whether Xofluza or another medication is appropriate. Same-day consultations are available.
- Receive your prescription electronically. If approved, your Xofluza prescription will be sent electronically to the pharmacy of your choice. No office visit needed.
- Take the medication as directed. Follow the dosing instructions and avoid products containing polyvalent cations around the dose. Rest and stay hydrated. Seek urgent medical care if you develop difficulty breathing, confusion, or worsening symptoms.
No health insurance or subscription is required for the consultation itself. Medical providers are available now.
More Xofluza Information
Last updated September 26, 2026. Given the evolving nature of medicine and science, this information might not be accurate and should not be construed as medical advice or diagnosis / treatment recommendations. Please consult a licensed medical provider if you have additional questions. Please call 911 immediately or go to the nearest emergency room if you believe you are experiencing a medical emergency.